COVID-19 is a key aim of GenOMICC
Susceptibility to COVID-19 is almost certainly, in part, genetic. GenOMICC can find the genes that cause susceptibility, which may help us to prioritise treatments to respond to the global crisis.
In particular, we aim to recruit every intubated patient with COVID-19. If you need to prioritise, please start with the youngest.
GenOMICC in Canada
Recruitment to GenOMICC is easy and urgent. We need to do this at very large scale in order to get fast answers that may alter the delivery of critical care medicine. International collaboration will be crucial in acheiving this aim. Using our open-source approach, investigators have adopted the GenOMICC protocol for use in Canada. Contact us at david.maslove@queensu.ca to express interest in establishing recruitment at your site.
Recruitment requires consent, a single blood DNA sample and a very short online CRF (see example recruitment procedures here).
Summary
We ask these questions of every patient:
- are they critically ill? (need for continuous monitoring/mechanical ventilation)
- is the primary cause of illness eligible? (e.g. COVID-19, Influenza, Pneumonia, Emerging infections, Burns, Cellulitis, Pancreatitis)
- (for non-COVID patients) are they under 70 and functionally-well?
If the answers are yes, we:
- obtain consent
- get a blood sample
- complete online CRF
Help with recruitment
We know that every ICU is under unprecedented pressure. We are ready to help wherever we can - please get in touch with us any time for assistance: david.maslove@queensu.ca. We're making this as simple as we can:
- Screening: every ICU COVID patient is eligible.
- CRF: We've simplified this to eligibility, consent and outcome. That's all.
- Consent: We'll help to coordinate appropriately-trained staff in your hospital to help you by getting telephone consent.
Canadian Investigators
Funding
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